Based on an understanding of pharmacology, medicinal chemistry and human physiology, this unit studies the factors influencing the pharmacokinetics and pharmacodynamics of drugs, and the application of this information to optimise the therapeutic usefulness of drugs in clinical practice. Topics include: the calculation and interpretation of pharmacokinetic parameters, pharmacokinetic processes and their physiological determinants, estimating drug dosage requirements in clinical practice; therapeutic drug monitoring; and an overview of sources of inter-patient variability in pharmacokinetics such as disease states, age, pregnancy and lactation.
Prescribed Text - basic PHARMokinetics